Russell Williams Email & Phone Number

Washington, DC, US

Led and managed a team in exploratory research to optimize proprietary assay components.Utilized Oxford nanopore sequencing in challenging sample types, necessitating custom sample preparation and analytics.Designed adaptive R and Python pipelines to meet the analytical needs of exploratory research projects, leveraging machine learning via Keras.Innovated.

Rockville, Maryland, United States

• Supervised production team responsible for processing 250,000 samples/year using Next-Generation Sequencing and microarrays.
• Implemented RNA sequencing at production scale.
• Performed data review and troubleshooting for NGS and microarray projects.
• Implemented protocol improvements to lower cost and processing time while increasing data integrity.

Kinshasa, Congo (DRC)

• Piloted a nanopore sequencing pipeline for retrovirus sequencing infield conditions.
• Performed sample management and statistical analysis for serologystudies on Ebola survivors and health care workers.

Gaithersburg, MD

• Developed clinical next-generation sequencing assays performed on 300,000 samples per year in CAP/CLIA accredited laboratories.
• Optimized SOPs to reduce cost and turnaround time and eliminate opportunities for user error.
• Performed data-driven troubleshooting of production-scale protocols.
• Evaluated new technologies for adoption.
• Built custom R and Python pipelines for standardizing data analysis

Baltimore, Maryland Area

• Designed and executed research projects that demonstrated the involvement of novel factors contributing to prostate cancer metastasis
• Guided investigations using expertise in gene expression analysis
• Developed R-based pipeline for gene expression data analysis used in multiple projects.

Washington D.C. Metro Area

• Designed and executed dissertation research that identified two genes as novel factors contributing to metastasis in colon cancer, and characterized their signaling pathways
• Specialized in identifying significant patterns in gene expression by analyzing large data sets
• Collaborated with investigators at multiple institutions, applying my expertise with data analysis and laboratory techniques to a variety of biological contexts
• Supervised and trained multiple lab members, including other doctoral candidates, in data analysis and molecular biology techniques

Raleigh-Durham, North Carolina Area

• Department of Radiation Oncology
• Conducted experiments to identify proteins associated with hypoxia in tumors, with particular interest in the cellular response to intermittent transient hypoxia
• Assisted with the creation of stably transfected cell lines using plasmids coding for fluorescent proteins under the control of a hypoxia-responsive promoter

Raleigh-Durham, North Carolina Area

• Managed breeding and genotyping for mouse colony of over 30 transgenic lines, overseeing the foundation of four additional hybrid lines that enabled a new series of experiments
• Conducted experiments to determine the immune phenotype of transgenic mice
• Supervised day-to-day laboratory operations and student assistants

Ph. D., Biomedical Science

B.S.E., Biomedical Engineering

Bachelor Of Engineering - Be, Biomedical/Medical Engineering