Ricardo Morales Email & Phone Number

United States

Analytical Development

• Developed LC/MS/MS assays for compounds in plasma and other matrices, and conducted pharmacokinetic analyses to rank potential drug candidates
• Bioanalytical laboratory lead to assure the pharmacokinetic studies proceeded according to established priorities
• Analyzed over 460 PK studies annually with very low turnaround time
• Improved laboratory procedures to streamline workflow and increase sample throughput; achieved a 2-fold increase in studies over a 3 year period with the same number of FTEs
• Developed methods and conducted experiments in support of development candidates o Whole blood partitioning o Sample preparation methods to stabilize intermediate metabolites o Analysis of highly polar metabolites via.
• Collaborated studies between bioanalytical, medicinal chemistry and pharmacology

• Developed LC/MS/MS assays for quantitative analysis of drug and metabolite concentrations in different matrices to support pharmacokinetic and toxicokinetic studies
• Processed and reported bioanalytical results to meet aggressive timelines which drove key decision making
• Maintained laboratory and instruments to full functioning status
• Presented concise and well organized data at research meetings
• Helped prepare accurate technical reports, project summaries, protocols, and data compilation for patent submissions
• Maintained a high level of data integrity and helped implement a formalized QC review system and research database

• Monitored and improved the quality of data to ensure laboratory meets or exceeds company standards
• Routinely collaborated with laboratory manager and chemists to establish protocols to increase the efficiency of various metabolite separation assays using HPLC, GC, and LC/MS
• Responsible for creating and accounting for the inventory of controls and standards used in the quantification of lipids and other metabolites
• Experienced in assay and instrument troubleshooting
• Assisted lab manager by leading/mentoring other chemists in daily laboratory functions
• Trained laboratory technicians to maintain sufficient throughput and quality standards