Sara Imboden Email & Phone Number

Agoura Hills, California, United States

Agoura Hills, California, United States

T-cell enhancement

Lin Laboratory - MechanobioengineeringResponsibilities:• Successfully led, conceived, and designed multiple research projects independently • Planned and executed experiments, analyzed data, wrote progress reports to communicate findings• Human/mammalian cell culture, immunofluorescent staining (ELISA) & imaging of MSC and LNCaP samples• Collaborated with several team members and laboratories to address issues on the field of research

Los Angeles, California, United States

Lin Laboratory - MechanobioengineeringJob duties:• Maintained and differentiated multiple human/mammalian cell lines (e.g. hMSC, LNCaP, MDCK) through serial passaging and cryopreservation, while investigating the effects of novel compounds on proliferation, differentiation and viability.• Performed and optimized immunofluorescent staining protocols (ELISA) for 20 different proteins resulting in increased image clarity and resolution of 2D and 3D samples.• Acquired high quality images of over 150 samples using bright-field, fluorescent and confocal microscopes.• Utilized quantitative microscopy to study changes in cell morphology & protein expression in response to various stimuli with a focus on cell heterogeneity, senescence (hMSC) and hypoxia-related necrosis (LNCaP).• Planned, prepared, documented and conducted laboratory experiments independently.• Created custom scripts and programs (Python, ImageJ) to automate and accelerate data analysis tasks.• Performed extensive literature review, successfully interpreted experimental results and presented them weekly. • Wrote and edited three scientific manuscripts according to the specific journal formats (LaTex, Microsoft Word)• Supervised and successfully trained multiple undergraduate and graduate students on proper research methods• Collaborated with multiple team members and laboratories to address issues on the field of researchProjects:• Investigating Heterogeneities of Live Mesenchymal Stromal Cells Using AI-based Label-free Imaging• AI-based Microscopy Assessment of Senescence in Human Mesenchymal Stromal Cells • Ensemble-based Trustworthy AI Image Translation for Microscopy-based Cell Phenotyping• Microwell-based Flow Culture Reveals Hypoxia-Masked Phenotype and Drug Response in Prostate Cancer Spheroids

Zurich, Switzerland

"3D registration of CT images and photogrammetry models for open spine surgery."• Developed deep learning-based algorithms for intraoperative registration of human vertebrae• Programmed a C++ plugin for a medical image analysis software (ImFusion)• Performed error analysis and troubleshooting independently

Zurich, Switzerland

Course "Mechanobiology: Implications for Development, Regeneration and Tissue Engineering"• Maintained a course website with up-to-date lecture notes and assignments for 200 students, ensuring timely access to course materials

Zurich, Switzerland

Course "Materials and Mechanics in Medicine"• Taught class of 30 undergraduate students in a weekly exercise session

Urdorf, Zurich, Switzerland

Master Of Science - Ms, Health Sciences And Technology

Major: Medical Technology (US equivalent is Biomedical Engineering) Graduated with distinction

Bachelor Of Science - Bs, Health Sciences And Technology

Education record