Smita Agrawal Email & Phone Number

Serving as an independent consultant, providing strategic guidance and expert insights to life sciences companies on genomics, real-world data, and the application of AI for deriving actionable insights from healthcare data.

Bengaluru, Karnataka, India

𝐏𝐫𝐨𝐝𝐮𝐜𝐭 𝐎𝐰𝐧𝐞𝐫, 𝐆𝐞𝐧𝐨𝐦𝐞360 𝐚𝐭 𝐂𝐨𝐧𝐜𝐞𝐫𝐭𝐀𝐈As the Product Owner of ConcertAI's Real-World Clinicogenomics data product, Genome360, my team and I were responsible for:𝐒𝐭𝐫𝐚𝐭𝐞𝐠𝐢𝐜 𝐕𝐢𝐬𝐢𝐨𝐧: Leading the overall strategic vision for Genome360, including the design and conceptualization of the data model, and the development of an NLP-assisted curation interface.𝐂𝐮𝐫𝐚𝐭𝐢𝐨𝐧 𝐓𝐫𝐚𝐢𝐧𝐢𝐧𝐠 𝐚𝐧𝐝 𝐐𝐮𝐚𝐥𝐢𝐭𝐲 𝐂𝐨𝐧𝐭𝐫𝐨𝐥: Training… Show more 𝐏𝐫𝐨𝐝𝐮𝐜𝐭 𝐎𝐰𝐧𝐞𝐫, 𝐆𝐞𝐧𝐨𝐦𝐞360 𝐚𝐭 𝐂𝐨𝐧𝐜𝐞𝐫𝐭𝐀𝐈As the Product Owner of ConcertAI's Real-World Clinicogenomics data product, Genome360, my team and I were responsible for:𝐒𝐭𝐫𝐚𝐭𝐞𝐠𝐢𝐜 𝐕𝐢𝐬𝐢𝐨𝐧: Leading the overall strategic vision for Genome360, including the design and conceptualization of the data model, and the development of an NLP-assisted curation interface.𝐂𝐮𝐫𝐚𝐭𝐢𝐨𝐧 𝐓𝐫𝐚𝐢𝐧𝐢𝐧𝐠 𝐚𝐧𝐝 𝐐𝐮𝐚𝐥𝐢𝐭𝐲 𝐂𝐨𝐧𝐭𝐫𝐨𝐥: Training curators, processing molecular pathology data, and conducting final quality checks.𝐏𝐫𝐨𝐝𝐮𝐜𝐭 𝐑𝐨𝐚𝐝𝐦𝐚𝐩: Maintaining the product roadmap and patient counts across eight tumor types.𝐒𝐚𝐥𝐞𝐬 𝐚𝐧𝐝 𝐌𝐚𝐫𝐤𝐞𝐭𝐢𝐧𝐠: Developing sales and marketing collateral, creating product summary dashboards, and preparing product summary presentations for each release.𝐒𝐮𝐩𝐩𝐨𝐫𝐭: Supporting sales and customer success teams with pre-sales and post-sales queries.𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡: Conducting research and publishing studies to demonstrate the utility of Genome360 for translational research.𝐓𝐞𝐚𝐦 𝐋𝐞𝐚𝐝𝐞𝐫𝐬𝐡𝐢𝐩 𝐚𝐧𝐝 𝐈𝐧𝐧𝐨𝐯𝐚𝐭𝐢𝐨𝐧I established and led a team of clinical and bioinformatics scientists, responsible for:𝐋𝐢𝐧𝐞 𝐨𝐟 𝐓𝐡𝐞𝐫𝐚𝐩𝐲 𝐌𝐨𝐝𝐞𝐥𝐬: Clinical definition, validation, and overall product ownership of Line of Therapy models across all ConcertAI data products.𝐍𝐋𝐏 𝐌𝐨𝐝𝐞𝐥𝐬: Providing all clinical inputs, including definitions and maintaining knowledge bases, as well as monitor the performance and validation of all NLP models for the development of NLP enhanced data products.𝐁𝐢𝐨𝐢𝐧𝐟𝐨𝐫𝐦𝐚𝐭𝐢𝐜𝐬 𝐏𝐢𝐩𝐞𝐥𝐢𝐧𝐞: Setting up and managing a bioinformatics pipeline for the analysis of Whole Exome Sequencing (WES) and Whole Transcriptome Sequencing (WTS) data.𝐑𝐞𝐬𝐞𝐚𝐫𝐜𝐡: Conducting research and publishing studies using our various real-world datasets, both independently and in collaboration with our clients. Show less

Bengaluru, Karnataka, India

Bengaluru Area, India

- Head the clinical data analysis team: Responsible for analysis of DNA-Sequencing data generated in Strand's clinical genomics labs. This includes data from somatic cancer as well as various inherited diseases and whole exome panels.- Guide the product design for StrandOmics, Strand's clinical interpretation and reporting software.- Involved in collaborative research projects in personal genomics with various hospitals/research institutions.

- Performed a collaborative basic research study involving extensive experimental as well as computational efforts. This led to the identification of a novel DNA element and a binding partner involved in recruitment of a key transcription factor to regulatory sequences in the context of T-helper cell differentiation. - Leading a project in collaboration with Constellation Inc. (epigenetics based drug discoverycompany headquartered in Boston, MA) to discover novel drug targets for… Show more - Performed a collaborative basic research study involving extensive experimental as well as computational efforts. This led to the identification of a novel DNA element and a binding partner involved in recruitment of a key transcription factor to regulatory sequences in the context of T-helper cell differentiation. - Leading a project in collaboration with Constellation Inc. (epigenetics based drug discoverycompany headquartered in Boston, MA) to discover novel drug targets for auto-immune disorders like Rheumatoid Arthritis (RA), InflammatoryBowel Disease (IBD) etc.– Collaborating on other projects within the group to analyze and build testable hypotheses from large scale biological datasets including ChIPseq, microarray and RNAseq data. Show less

– Studied the role of alternative splicing in disease onset and progression leading to cerebellarneurodegeneration in a mouse model of spinocerebellar ataxia type 1 (SCA1).

– Experimentally elucidated the role of the Notch and Wnt signaling pathways in regulating cellfate decisions of hippocampal adult neural stem cells.– Computationally analyzed the Notch signaling network using deterministic and stochasticmodels to predict key components of the signaling pathway involved in cell fate switchdetermination.

Doctor Of Philosophy (Phd), Chemical Engineering

Minor in molecular cell biology

B.Tech, Chemical Engineering