Steven Horner work email
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Steven Horner is a Scientist at Takeda. He possess expertise in molecular biology, microbiology, immunology, cancer biology, biotechnology and 9 more skills.
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ScientistTakedaCambridge, Ma, Us -
Sr. Research Associate IiMoma Therapeutics Jun 2022 - Oct 2024Cambridge, Massachusetts, United States -
Senior Research AssociateBroad Institute Of Mit And Harvard Oct 2020 - Jun 2022Cambridge, Massachusetts, United StatesLead protein scientist on early stage small molecule drug discovery campaigns, focusing on construct design, protein purification, biochemical/physical characterization and protein:protein or protein:ligand interaction assays. My work enables high-throughput and NMR fragment-based screens, and I develop x-ray crystallography systems to structurally enable projects and aid SAR in hit-to-lead pipelines. I research and develop protein engineering and cell pharmacology techniques in order to modulate PTMs or co-factor loading in mammalian, insect, and E. coli expression systems. -
Research Associate IiiBroad Institute Of Mit And Harvard Jul 2018 - Oct 2020Cambridge, Massachusetts, United StatesProtein purification and x-ray crystallography for a lead optimization drug discovery target in oncology. Screened and optimized crystallographic conditions and developed soaking system for natural and therapeutic ligands at < 2 A resolution. Developed SPR assay to characterize protein-protein interactions in presence and absence of ligands. Generated stable complexes suitable for Cryo-EM at < 3 A resolution.
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Research Associate IiBroad Institute Of Mit And Harvard Jan 2017 - Jul 2018Cambridge, Massachusetts, United StatesProtein purification at the hundred milligram scale and biophysical assay support for a hit-to-lead drug discovery campaign on a cardiovascular target, generating constructs to drive SAR via x-ray crystallography, SPR, ITC, DSC, MST, NMR (2H, 13C, 15N).
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Laboratory Technician IiiUniversity Of Rochester Medical Center May 2015 - Dec 2016Rochester, New York AreaVector design and expression, protein purification, binding assays, and x-ray crystallography in Dr. Clara Kielkopf's structural biology laboratory at the URMC's Biochemistry and Biophysics Department. In addition to heading multiple research projects, I trained new members and was responsible for purchases, maintenance, repairs and certifications for our group. -
Laboratory Technician IUniversity Of Rochester Medical Center Nov 2013 - Apr 2015Rochester, New York AreaDeveloped and characterized a micro-arrayed, chip-based biophysical assay for pneumococcal serotyping using Arrayed Imaging Refelectometry in the laboratory of Dr. Ben Miller.
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Undergraduate ResearcherRochester Institute Of Technology 2009 - 2011Research into the NF-kB pathway and its roll in VSV infection. Cloned mammalian expression vectors, managed HeLa and L929 mammalian cell lines, performed transfections, infections, and qRT-PCR experiments.
Steven Horner Skills
Steven Horner Education Details
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Molecular Bioscience And Biotechnology
Frequently Asked Questions about Steven Horner
What company does Steven Horner work for?
Steven Horner works for Takeda
What is Steven Horner's role at the current company?
Steven Horner's current role is Scientist.
What is Steven Horner's email address?
Steven Horner's email address is sh****@****ute.org
What schools did Steven Horner attend?
Steven Horner attended Rochester Institute Of Technology.
What are some of Steven Horner's interests?
Steven Horner has interest in Human Rights, Education, Environment, Poverty Alleviation.
What skills is Steven Horner known for?
Steven Horner has skills like Molecular Biology, Microbiology, Immunology, Cancer Biology, Biotechnology, Pcr, Elisa, Gel Electrophoresis, Transfection, Hybridoma, Tissue Culture, Microarray Analysis.
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Steven Horner
Registered Somatic Movement Therapist, Creator, And Facilitator At Ape . Men; Improvised Movement Performance ArtistSan Luis Obispo, Ca1steven-horner.com -
Steven Horner
Cincinnati Metropolitan Area3capitalone.com, pinnsg.com, pinnsg.com5 +170344XXXXX
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Steven Horner
Retired, Formally Principal, Horner & Associates, Llc -Organizational Effectiveness ConsultantsHarleysville, Pa
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