Sunil Tomar Email & Phone Number

San Diego, CA, US

San Diego, California, United States

• Team Lead for development of new strategies and methods for Potency Assays’ Matrix-based characterization of CAR-T DP lots through cell-based and immunophenotyping-based DP lot release and FIO characterization assays.
• Developed 2+ new lot release potency assays per ICH Q2 R2 guidelines from end-to-end, including strategy design, method development, tech transfer to QC, authoring qualification protocols and supporting qualifications.
• Led strategy and methods development for different novel, rapid, quantitative, cell health assays, with significant improvement in sensitivity over current industry standard methods for process characterization.
• Strong believer in team-based, collaborative approaches, with a problem-solving mindset. Experienced in working closely with QC/QA teams for transfer of methods and supporting investigations, authoring documents such.

Ann Arbor, Michigan, United States

• Led immunology research projects in food allergy from inception, design and execution to publications, primarily focusing on cellular cross-talk between mucosal mast cells, ILC2s and Th2 cells. Ex vivo multi-color.
• Described multiple novel cytokine signaling pathways and cellular origins for development of unique food allergy driving mucosal mast cells.
• Led immune cell-analyses-based discovery of biomarkers uniquely expressed in anaphylactic mice and humans in response to oral food allergen exposure.
• Provided mucosal immunology subject matter expertise in multiple research projects through intra-lab and inter-lab collaborations by guiding in vivo and in vitro study designs, leading critical study executions and.

Cincinnati, Ohio

• Led tumor immunology research projects off the ground, focusing on self vs foreign (neo) antigen-specificity of tumor infiltrating cells (TILs) in two different solid tumor mouse models.
• Studied phenotype- and function-based activation, exhaustion status of TILs and tumor-specific CD4, CD8 T cells in draining lymph nodes and secondary lymphoid organs.
• Gained expertise in whole blood phenotyping, immune cell isolation from several lymphoid organs, ex vivo functional analyses, 12+ color immunophenotyping, ex vivo functional analyses and cell sorting.
• Discovered previously unknown cell-intrinsic effect of IL-4 signaling on development and function of specific subset of proallergic mast cells, through bone marrow chimera models and in-depth analyses of several.

Indiana University School Of Medicine, Bloomington

• Gained expertise in 3D-organotypic in vitro culture system to study cellular interactions in tumor microenvironment.
• Led the research to identify the role of a ETS family transcription factor, ETS-1 in the metastasis of ovarian cancer in mouse xenografts models.
• Collaboratively contributed to functional characterization of several high-grade serous ovarian cancer cell lines through metastases associated functions like migration, invasion, colony formation and Epithelial to.
• Contributed to cross- institutional collaborative studies, to identify the role of miR-193b in regulating ovarian cancer metastasis.

• Performed research in a Microbiology lab under the mentorship of a PhD student.
• Processed patient specimens to obtain samples for ELISA to detect Clostridioides difficile (C. diff) associated diarrhea (CDAD)
• Processed patient specimens to obtain DNA samples for PCR to detect CDAD
• Performed Biochemical and culture testing to identify the specific microbial stain of Clostridium difficile, responsible for CDAD

Doctor Of Philosophy (Phd), Biomedical Sciences

Activities and Societies: Immunology Journal club member 2009-2014Doctoral Dissertation Novel therapeutic approaches to ameliorate acute.

Bachelor Of Technology (B.Tech.), Biotechnology