Nathan Walsh Email and Phone Number
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I am a leader in digital for biotech and pharma. I have managed the Informatics, Biology, Applications and IT Departments for companies ranging from start-ups in biotechnology to pharmaceutical and diagnostic device manufacturers. I work as part of the senior executive teams, responsible for scientific direction based on my extensive bench experience with DNA, RNA, genome editing, pathways, proteins, peptides, and oncology. My statistical experience includes library analysis, software design and DNA modeling. I manage internal groups, cross matrix teams and outside contract companies. I make and adhere to budgets and timelines, plan computational resources, infrastructure and network growth.Specialties: Management, Biological/Chemical Informatics, Software Development, Biophysics, Statistics
Tetrascience
View- Website:
- tetrascience.com
- Employees:
- 149
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Tetrascience
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Targeting Head Of Informatics Role | Independent ConsultantSeeking New Opportunities Jun 2024 - Present
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Executive Director Of Quantitative BiologyModerna Sep 2023 - May 2024Cambridge, Massachusetts, Us🔹 Drove innovation and efficiency by providing strategic guidance for the genomics department🔹 Prepared for future throughput and technologies by collaborating with cross-functional teams to integrate robotic plate handling and AI/ML tools into NGS Prep🔹 Managed a group of informatics scientists to build tools and analysis pipelines🔹 Improved time to result from 4 hr/run to 20 min/run with improved accuracy by leading a team of informatics scientists in developing advanced tools and analysis pipelines using nextflow parallelization🔹 Allowed searching and meta-experiment analysis of CRISPR Cas, DSB, Base Editors and Prime Editors by developoing a comprehensive registry for guide RNAs, nucleases, and amplicons🔹 Allowed existing workflows to communicate with new databases by building integrated SDKs🔹 Provided universal guides so that the same formulation of LNP's could be used across mouse, human, and NHP experiments through guidance and oversight to my team -
Vice President Application And BioinformaticsLexagene May 2020 - Feb 2023Startup microfluidics manufacturer for automated sample-prep and PCR detection🔹 Brought technology to market as part of the Senior Team with CEO, CFO, and Head of Engineering🔹 Identified key markets are obstacles to uptake as a key liaison with Knowledge Leaders -Successfully released the MiQLab system for automated sample prep and qPCR🔹 Wrote python software for machine learning (AI) for bacterial detection, implemented required checks and automated builds of software before merging code changes🔹 Improved software testing/dev environments by rolling out the use of Docker images🔹 Successfully managed migration to AWS to store > 30 million records and > 4 million images while keeping data live and interactive and keeping current and projected AWS operational costs below $10/month🔹 Worked on FDA compliance for COVID-19 EUA until FDA restricted its approval process🔹 Brought 4 full panels to market (Bacterial-AMR, UTI, pathogenic GI, and Bioreactor)🔹 Brought Sensitivity from 500,000 down to <100 CFU/mL for biomedical testing🔹 Managed the growth and maintenance of 100's of different bacteria, protozoa, and fungi requiring BL2, import permits, and FDA/CDC approval for on-site storage and use of pathogens of concern
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Director Of Applications And BioinformaticsLexagene Jan 2018 - May 2020🔹 Turned a design into a working instrument by leading the Biology and Informatics teams🔹 Designed and evaluated applications (PCR assays) for multiple markets🔹 Focused company on Veterinary Health, where expectations matched throughput and performance -Wrote python software for bacterial detection, image analysis, instrument simulation, and the main dashboard for tracking runs on instruments across the country🔹 Worked jointly with the Engineering team to identify and fix weaknesses in the MiQLab system -Implemented a continuous improvement of existing panels and established pipeline for new panels -Designed and oversaw the development of more than 100 specific PCR tests🔹 Designed, implemented and maintained databases in both RDBMS and NoSQL on virtual servers and at AWS
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Head Of Bioinformatics/Software Dev'T Mgr IiBio-Rad Laboratories Jan 2016 - Dec 2017Hercules, Ca, UsMicrofluidics device maker for next-generation sequencing with over 150 person staff🔹 Part of the Senior Team with full directional decision over the entire Cambridge site🔹 Leader of the Informatics team responsible for genomic analysis on and off instrument🔹 System Integration Liaison for medical device across all departments🔹 Built world class Informatics team through hiring, mentoring and building opportunities for my team🔹 Integrated the Informatics team from a silo into a core resource embedded in most projects🔹 Managed the building of identification, clustering, graph theory, and sequencing algorithms🔹 Increased from 50% to 90% the identification rate of microfluidic drops🔹 Drove the false positive rate from 20% to 1%🔹 Directed the building of tools and websites for ordering, manufacturing, in-house data analysis🔹 Developed a pipeline for DNA multiplex primer design and probe specificity -
Sr. Director, Informatics And ItEnsemble Therapeutics Corporation Jun 2006 - Jan 2016🔹 Manager of two CRO's (IT and DNA Sequencing)🔹 Formulate and oversee projects, timelines, deliverables of CRO's🔹 Implemented new computational methods to assign statistical significance to hits🔹 Devised and implemented new strategies for evaluating reproducibility and specificity of hits🔹 Generated lists of hits and presented results to Senior Management🔹 Designed DNA sequences compatible with “DNA Programmed Chemistry”🔹 Automated the processing of selection data from acquisition to hit lists🔹 Worked closely with Biologists and Informatics to create specific Oracle databases and user interfaces with embedded SQL🔹 Organized meetings and tracked progress of the Informatics team members🔹 Presented scientific results at external meetings🔹 In-house Software Requirement gathering, Development, and Production using C,C++,Perl, Python, Javascript, MATLAB or other languages as needed 🔹 Composed informatics and IT budget of >$500,000/year for a 30 person company🔹 Evaluated and managed the installation and maintenance of commercial software🔹 Purchased hardware and supervised installation and maintenance -
Senior Informatics ScientistEnsemble Discovery 2005 - 2006Cambridge, Ma, Us🔹 In charge of DNA sequence design for “DNA Programmed Chemistry”🔹 Translated data from Chemistry and Analytics to provide clear communication🔹 Set up inventory tracking and registration database and trained users🔹 Rolled out Electronic Lab Notebook (ELN) company wide🔹 In-house Chemistry Software Requirement gathering, Development, and Production🔹 Performed hardware installation and maintenance -
Research FellowHarvard Medical School Jan 2002 - Apr 2005Boston, Ma, UsManaged a Synthetic Biology Project designed to construct an in vivo counter including supervison and training of a rotation PhD studentCoordinated a proteomic mass spec project and identified protein complexes -
Research FellowBrigham And Women'S Hospital Jan 2002 - Apr 2005UsDesigned and implemented computational algorithms for identifying human enhancers using clustered microarray data
Nathan Walsh Skills
Nathan Walsh Education Details
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Massachusetts Institute Of TechnologyBiology (Biophysics) -
Brown UniversityBiochemistry
Frequently Asked Questions about Nathan Walsh
What company does Nathan Walsh work for?
Nathan Walsh works for Tetrascience
What is Nathan Walsh's role at the current company?
Nathan Walsh's current role is Executive Champion of Digital Systems for Genomics and Informatics.
What is Nathan Walsh's email address?
Nathan Walsh's email address is nw****@****ery.com
What is Nathan Walsh's direct phone number?
Nathan Walsh's direct phone number is +161749*****
What schools did Nathan Walsh attend?
Nathan Walsh attended Massachusetts Institute Of Technology, Brown University.
What skills is Nathan Walsh known for?
Nathan Walsh has skills like Biotechnology, Informatics, Biochemistry, Statistics, Dna, Bioinformatics, Drug Discovery, Molecular Biology, Chemistry, Life Sciences, Software Development, Project Management.
Who are Nathan Walsh's colleagues?
Nathan Walsh's colleagues are George Van Den Driessche, Emil Grama, Jan Winkelmann, Ivan Solt, Austin Corea, Cindy Nevers, Michael Mayers.
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