Nephroreduce

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This is a project led by the University of Bergen and funded by The Norwegian Seafood Research Fund (FHF). Kidney stones (often referred to as nephrocalcinosis) is currently one of the largest welfare issue in land-based salmon farming (The Norwegian Fish health Report, 2022). The overall goal of the project is to better understand how the salmonid kidney respond to changes in the rearing environment and how such changes may result in the formation of kidney stones. Result from the project may help farmers better understand the range of triggering factors associated with development of kidney stones. The project aims to develop preventive measures and provide “best practice” to the industry for overall reduction of kidney stones, thereby improving fish health and welfare. The project has the following sub-goals: 1. Determine what factors in water quality, feed and fish handling practices (e.g. transfer protocols) that may affect the prevalence of kidney stones. 2. Experimentally test our hypothesis regarding the proximate trigger mechanism (e.g large drops in CO2 levels) that initiate and may cause the formation of kidney stones. 3. Integrate the macroscopical score performed at the facilities to histological findings, x-ray imaging and ultrasound to develop a universal scoring system for farmers. 4. Determine physiological and molecular changes in kidney, urine and blood (e.g molecular transporters and biochemical analysis) of healthy fish and kidney stone afflicted fish 5. Test preventative measures (feed and rearing conditions) to reduce and/or prevent the development of kidney stones. 6. Provide “best practice” protocols to industry to reduce the prevalence of kidney stones. The project have several research and industry partners: The University of Gothenburg, The University of British Columbia, Nofima, Moredun Research Institute, Patogen AS, Skretting ARC, Aquaticode, Mowi, Cermaq, Lerøy, Hofseth, Osland, Hima Seafood and NCE Seafood Innovation.

Company Details

Employees
8
Founded
-
Address
Bergen, No
Industry
Research Services
NAICS
Scientific Research and Development Services
Research and Development in the Physical, Engineering, and Life Sciences
Research and Development in the Physical, Engineering, and Life Sciences (except Nanotechnology and Biotechnology)
HQ
Bergen
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