Adrian Smith Email & Phone Number

Milton Keynes, Gb

Bedfordshire

Development and production of a semi-automated pipeline for annotation of Whole Genome Sequences. This includes gene prediction by several algorithms, BLAST and InterProScan runs, pathway annotation and subsequent protein family analysis. Design and management of project to identify optimum primer sets to use for next generation sequencing of fungal amplicons, including identification of primer pairs from literature, and design of novel ones. This project has included evaluation of the… Show more Development and production of a semi-automated pipeline for annotation of Whole Genome Sequences. This includes gene prediction by several algorithms, BLAST and InterProScan runs, pathway annotation and subsequent protein family analysis. Design and management of project to identify optimum primer sets to use for next generation sequencing of fungal amplicons, including identification of primer pairs from literature, and design of novel ones. This project has included evaluation of the primer sets from NGS and recommendation of the most appropriate to select for future fungal analysis.Design and implementation of Bioinformatics analysis pipelines for NGS data used in microbiomics, metagenomics and transcriptomics research.Production of novel, leading edge Fungal taxonomy classifier for phylogenetic analysis of NGS results.Provide recommendations as to the IT infrastructure required for high throughput sequencing studies.Project management of work streams enabling Cloud computing for NGS data processing.Management of major collaboration with external experts in NGS data QC and denoising.Implementation of algorithms and software into in-house NGS data processing pipeline, including utilisation of 32-node high-performance computing cluster, and subsequent automation of the workflow. Review and recommendation of bioinformatics software and processes for the step up to Metagenomics analysis.Literature surveys and bioinformatics analysis of unexpected laboratory results to offer possible novel explanations.Implementation of a Platform for Data Driven Biology research in R&D. Show less

Bedfordshire

Amateur Sports Club.

Bedfordshire

Amateur Mid Week Cricket Club.

Corby

During my tenure i have overseen successful noise mitigation campaign against major dual carriageway, building of new community centre, and two very successful charity fun days.

Bedfordshire

Performed literature reviews of metabolism to identify key papers for providing numerical data for cell models.Development of a semi-automated ontology building method to allow classification of literature for quick searching and hypothesis generation.Management of external collaborations

Bedfordshire

Analysis of genes and proteins associated with specific SNPs, including identification, annotation, synteny analysis and gene prediction.Protein characterisation, including multiple alignments, domain mapping and motif identification. Assembly of data for patent applications, including literature searching.Tiling array design work for analysis of transcription of a specific region of the human genome.

Completing bioinformatics requests arising during the early stages of drug discovery.Analysis of large data sets.SNP analysis, multiple alignments, gene annotation and gene predictions.Development and improvement of data analysis tools and in-house web based applications

Master Of Science, Bioinformatics

Bachelor Of Science (Bsc), Biomedical Sciences, General, 2:1

Activities and Societies: Sheffield Hallam University RAG; Sheffield Hallam Amateur Dramatics and Entertainment society Was awarded.