Christy Cooper Email and Phone Number

SummaryTwenty years of R&D experience in academia and industry (Purdue University, Eli Lilly & Company, Dow AgroSciences, Charles River Laboratories, BD Biosciences), co-op experience, collaborative research, and consultation. I am a flow cytometry scientist with a focus on clinical-phase research and development. My research at Purdue involved flow cytometry-based detection of rare leukemic blasts with stem-like repopulating potential and multi-drug resistant phenotypes in ex vivo studies using leukemia cells spiked into whole human blood at various frequencies as a model for minimal residual disease detection. At Charles River Laboratories I developed and validated 8-14 color flow cytometry immunophenotyping panels for small to mid-sized biotech clients in support of preclinical drug development and general toxicology studies. I worked as a Systems Verification Engineer at BD Biosciences and performed systems verification testing of new versions of FACSDiva, new workstation computers, and testing of various functionalities of the BD Research Cloud including the Panel Maker feature. Aditxt Therapeutics (Aditxt Inc) recruited me to Virginia to work on bringing flow cytometry capabilities to the company’s clinical testing site. I have validated bead-based SARS CoV-2 serology assays for antibody and neutralizing antibody detection. Experienced in mammalian cell culture, flow cytometry assays for cell surface antigen (CD) expression, ex vivo stimulation of various immune cell subsets in an antigen-specific and also non-specific manner, viability assessment, apoptosis evaluation, and ploidy determination. Fluorescence microscopy. Data analysis in WinList , FCS Express, and FlowJo, various Bioconductor/R packages. Familiar with Beckman Coulter and BD flow cytometers.Experienced in polymeric and metallic nanoparticle synthesis and with surface functionalization of nanomaterials. Proficient in colloid characterization methods including dynamic light scattering (DLS), zeta potential measurement, turbidimetric titration, and size exclusion chromatography (SEC). Specialties: Nanomaterials construction/characterization Multicolor (6-20 color) flow cytometry method development (preclinical general toxicology assessment of various immune cell subsets in primates, humans, rats, and mice, viability, apoptosis, nuclei counting, ploidy analysis, immunophenotyping)Fluorescence microscopy w image analysis using ImageJMammalian cell cultureEquipment training and maintenanceGeneral laboratory management Technical writing