Jacqueline Smith Email & Phone Number

Cambridge, Massachusetts, United States

Lead the development of new products and technologies within a dynamic and growing environment. Introduce scalability and reliability in new ways by communicating needs to cross functional teams. Generate road maps to build project milestones and identify target dates. Ensure timelines are met by removing blockers for dependent groups and identifying areas that need resource management.Act as scientific technical expert to advise growth and development opportunities in high level project planning and continuous improvement efforts. Primary focus on CRO improvement for maintaining a competitive edge and improving the company’s location in the multi- ‘omic data generation market frontier.

Cambridge, Ma

Managed over 10 permanent direct reports and dozens of temporary individuals involved with cross training of functional teams.Demonstrated methods scalability in development of high throughput workflows.Improved existing technologies and investigated novel approaches with unbiased methods.Utilized advanced statistical analysis to determine potential paths forward with production goals. Harnessed experience with bench level work to transition into a mentoring role with ability to support science and people. Managed laboratory day to day operations, supply chain needs, and space planning within a dynamic growing laboratory. Adapted health and safety management within the lab in line with changing global conditions. Maintained checks and balances of spending to keep costs within defined budget.Managed a group of testing personnel following established standard operating procedures for specimen handling and processing, test analysis, reporting of results and prompt record-keeping.Ensured that all group members adhere to quality control policies and document all quality control activities, instruments and procedural calibrations, reagent preparation and testing, and instrument maintenance performed.Identified problems that may adversely affect test performance, executed authorized corrective action, and notified key individuals.Detected and implemented changes when test KPIs did not meet expectations. Documented all corrective action in appropriate systems with proper notifications.Assisted in multi-year project launch for improvements following CLIA / CAP regulations to provide a full end to end clinical return of results product with direct patient impact in collaboration with the PE-CGS program.

Cambridge, Massachusetts, United States

Act as a liaison between technical lab personnel and project managersMember of COVID-19 testing launch committeeScientific research presentation at AGBT conference 2019Cell culture development for use as internal Germline control DNA and haploid iPSCProvide support in on-boarding and training new staff and provide ongoing guidance for system and processes.Supervise and support day-to-day activities performed by the teamMentor team and guide long term projects to align with company wide goalsSupport CAPA development plans and perform effectiveness checks after root cause correction.Change control management (utilized program “MOCHA”) and communication.Monitor KPI trends and identify areas in need of improvement.Provide leadership, direction, and mentorship to direct reports.Responsible for independently managing and executing own projects.Escalate issues or needs for support/resources to management when necessary.

Cambridge, Massachusetts, United States

Wet bench work maintaining competency of over 20 complex protocols for the genomics platform.Protocols ranged from simple DNA extraction to in depth RNA and DNA co extraction processing from source materials such as Blood, Saliva, Buccal Swabs, Cell Pellets, Stool, FFPE, Frozen Tissue.Skilled in Next Generation Sequencing (NGS) techniques for Whole Genome Sequencing; including the implementation of PCR-free processing.Mainly focused on production level goals to produce nucleic acid for sequencing protocols.Executed continuous process improvement and development with significant work in RNA QC and DNA extraction from saliva methods development.Lean Six-Sigma Yellow Belt Course Completion and Utilization.CLIA and BL2+ lab safety training, practice, and documentation.

Cambridge, Massachusetts, United States

Broad Clinical Labs (BCL) is a subsidiary of the Broad Institute of MIT and Harvard that provides a range of research and clinical services — including CAP-accredited and CLIA-certified genomic data generation and advanced genomic analysis — both for the Broad research community and for the rest of the world.The Change Management team is responsible for working closely with production laboratory teams to identify areas for continuous improvement projects and supporting successful implementation. Serving as a resource to assist process development lab technicians in organizing Continuous Improvement (CI) efforts and Design of Experiments (DOE). Acting as a technical expert to assist with troubleshooting experiments when necessary. Mentoring PDAs on best practices pertaining to CI, Change Management (CM) and necessary documentation. Assisting and leading new workflow integrations and product development efforts. Specific impact with launching clinically validated high scale blood extraction increasing processing throughput x3.Working closely with the Informatics team, in combination with the lab, to complete UX scenario and user scenario requirement documents to better understand the scope of a LIMs request and developing user acceptance testing (UAT) plans prior to implementation.Specific impact with organizing smooth transition from three storage software systems into one unified storage system that meets the diverse needs of end to end laboratory production groups.

Needham, Ma

Exercised scene safety and BSI precautions. Demonstrated strong understanding of HIPPA guidelines and compliance. Assisted the community with appropriate level of care for the current condition. Aided higher level health care professionals to provide exceptional quality patient care for the greater Boston area. Utilized electronic and written records to perform detailed assessment on an individual, document condition in a written report and provide a real time oral overview of how the patient is presenting along with pertinent past medical history. Worked with EMT-B and EMT-P certified individuals during shifts including overnight coverage. Occasionally transported in teams when necessary. Specialized in transportation of female patients in need of emotional support, mental health evaluation, and counseling. Ability to deescalate situations when necessary to provide public assistance while maintaining situational awareness. Developed skills for negotiation with people experiencing diminished cognitive function to aid and assist them in improving their current health conditions.