Matthew Lo Email & Phone Number

Irvine, California, United States

•Leading a team of 4 graduate students to further develop a device with Mitsubishi Electric for optically measuring vitals and health status•Preparing documentation and organizing meetings with company liaisons, student team, and faculty advisor •Conducting literature review of measurable features and other potential optical methods•Organizing and documenting research and current prototype code in Python and C++•Designing new iteration of prototype with improved features and accuracy

Tucson, Arizona, United States

•Performing analysis on whole body and segmental angular momentum, utilizing statistical parametric mapping•Developing experimental study to look at the effects of carrying items on gait and arm motion. Will analyze in MATLAB deltoid muscle activation via EMG and arm swing characteristics via motion tracking. This study is currently IRB approved and preparing for trials

Tucson, Arizona, United States

•Designed MATLAB programs to analyze patient slip data•Analyzed slip data to determine significance of arm movement in regaining balance and countering changes in center of mass; patients slipped with their arms free or bound to their torso•Parsed data of slip patients regarding correlations between slip foot velocity and acceleration, and trunk and arm velocity, acceleration, and total excursion•Created analysis of motion tracking data to determine significance whole body and segmental angular momentum

•Leading team meetings, ensuring progress of each subteam, and preparing team for clinical study•Spearheading software development/algorithm design and legal subteams•Analyzing bruise phantoms for calibrating system and algorithm•Assisted in writing clinical protocol for a study which has received IRB approval

Irvine, California, United States

•Developing a novel device to spectrally detect, characterize, and age bruises for clinical and domestic abuse applications across all skin tones•Conducting literature reviews and designing algorithm in MATLAB to analyze hyperspectral bruise images•Analyzing bruise phantoms for calibrating algorithm with spectral characteristics of different dyesDesigning algorithms to characterize bruise spectra•Collaborating with and integrating work between the hardware, software, and clinical/phantom subteams to optimize testing and device development•Implemented code to streamline program file loading and data analysis for large image sets•Assisted in writing clinical protocol for a study which has received IRB approval•Created MATLAB program to generate simulated hyperspectral bruise images of different sizes with noise variations

Irvine, California, United States

•Leading subject data collection for physiological correlates of attention levels•Spearheading collaboration with the UCI School of Medicine to record mock clinical procedures•Created and troubleshooted new SOP for subject data collection

•Virtualizing clinical setting with LiDAR, photogrammetry, and Unreal Game Engine for virtual reality to improve medical education and training•Creating 3D navigable clinical space to increase clinical immersion with virtual reality utilizing Microsoft Azure Kinects with RGB and depth sensors•Conducting IRB-approved study to collect subject parametric data for assessing attention levels based on heart rate, pupil dilation, and eye tracking•Assessing attention levels juxtaposed across teaching modalities including standard video formats, 360º VR and volumetric video•Tested viability of different cameras and applications for scanning medical equipment and recording video in 3D for initial proof of concept, including Intel RealSense, Microsoft Azure Kinect SDK, ProCamera, Record3D, and Polycam•Lead tests to determine the minimum number of depth sensors for adequate overlap between cameras for optimal processing of 3D scans•Scanned equipment and mock clinical settings in the Medical Simulation Center at the UCI School of Medicine•Assisted data analysis of EEG data for potential features of attention correlates•Designed SOP for acquiring, editing, and exporting volumetric video•UROP Fellow (2021, 2022): wrote research proposals and presented at UROP symposium

Irvine, California, United States

•Working with a team to develop a novel balloon catheter device for improving the accuracy of stent placements•Organizing, scheduling, and documenting team meetings and tasks•Conducting literature review of pathophysiology of vascular stenosis, and current devices and research for treating these conditions•Designed and prototyped initial sensor design and user interface utilizing Arduino and MATLAB•Created calibration curve between balloon parameters and sensor outputs•Networked, interviewed, and shadowed with over 15 interventional cardiologists and cath lab staff across several institutions and hospitals, including UCLA, UCI, UCSF, and CACVI for customer discovery of clinical needs•Received 2023 UCI NSF I-Corps Grant for completion of the I-Corps program•Placed 2nd in 2022 National BMES-Medtronic Student Design Competition•Semi-Finalist in the 2023 UCI Stella Zhang New Venture Competition

United States

Looked at the relationship between Huntington’s Disease and its effect on huntingtin binding processes. Alzheimer’s Disease classification of vesicle progression in endolysosomal pathway for amyloid-β.•Cultured neuroblastoma cells with normal and pathological huntingtin expression and imaged with fluorescence microscopy to determine cell localization. Utilized SimFCS to analyze spectral data with 3 component analysis•Conducted background literature review on binding interactions of mutant and wildtype huntingtin protein with the cellular plasma membrane for initial experimental setup preparation•Researched cross-correlation to implement into and automated phasor analysis of local image correlation spectroscopy (PLICS) in python to characterize vesicle progression in the endolysosomal pathway in normal and exogenous amyloid beta conditions•Translated original PLICS algorithm from MATLAB into python to improve troubleshooting•Automated analysis including image thresholding to streamline data processing of image sets•UROP Fellow 2022: wrote research proposal and presented at UROP symposium

Irvine, California, United States

•Designed and prototyped plug device to reduce paravalvular leak associated with transcatheter aortic valve replacements•Reviewed literature on anatomy, physiology, and current devices and market for paravalvular leak and different applications of different potential materials•Conducted FMEA, and verification and validation testing of prototype with modeled vasculature to ensure proper filling of leak site and regulation of blood flow•UROP Fellow 2022, Chancellor’s Award for Excellence in Undergraduate Research: invited to present oral presentation for UROP at UCI. Only 30 teams were selected out of 300+ applicants.•2023 UCI BioENGINE Best Design Industry Award: selected as the top device in UCI BioENGINE senior design

Master Of Engineering - Meng, Biomedical Engineering

Bachelor Of Science - Bs, Biomedical Engineering: Premedical

Activities and Societies: BMES at UCI, National BMESSpecializations: Biophotonics, Micro and Nano Biomedical Engineering