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Matt Sinclair is listed as Ph.D. Candidate at University of Illinois at Urbana-Champaign at University of Illinois at Urbana-Champaign, based in Champaign, Illinois, United States. AeroLeads shows a matched LinkedIn profile for Matt Sinclair.
Matt Sinclair previously worked as Graduate Student Researcher - Computational Biophysics at University Of Illinois At Urbana-Champaign and Computational Chemistry Co-Op at Arrakis Therapeutics. Matt Sinclair holds Doctor Of Philosophy - Phd, Biochemistry from University Of Illinois Urbana-Champaign.
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I am an early career computational chemist with a passion for utilizing modern simulation and cheminformatics tools to advance drug discovery. My expertise is in molecular simulation, enhanced sampling techniques, free energy calculations, molecular docking, structure-based drug design and machine learning. My career goals include a desire to advance drug discovery through computational means to better serve the broader community.
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Characterizing antibiotic and native metabolite binding modes and interactions using molecular docking, free energy calculations and simulation.Probing cholesterol allostery and other protein-lipid interactions in membrane-embedded systems.
Waltham, Massachusetts, United States
Generation of native 3D RNA conformation from predicted structures leveraging available experimental data, markov state modeling and machine learning.Internalized several enhanced sampling workflows including adaptive sampling, simulated annealing, replica exchange and cosolvent molecular dynamics.
Coralville, Iowa
Production of a variety of buffers, solutions and cell media.Assisted product development and research teams with development of new buffer systems for purification of oligonucleotides and validation of new workflows.Developed inventory management algorithm to ensure on-time preparation and delivery of production materials.
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Matt Sinclair works for University of Illinois at Urbana-Champaign.
Matt Sinclair is listed as Ph.D. Candidate at University of Illinois at Urbana-Champaign at University of Illinois at Urbana-Champaign.
Matt Sinclair is based in Champaign, Illinois, United States while working with University of Illinois at Urbana-Champaign.
Matt Sinclair has worked for University Of Illinois At Urbana-Champaign, Arrakis Therapeutics, and Integrated Dna Technologies.
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Matt Sinclair holds Doctor Of Philosophy - Phd, Biochemistry from University Of Illinois Urbana-Champaign.
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