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Therapeutic antibody developer/ bio-assay developer/Consultant/ Oncology/Inflammation
Self-Employed
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Consultant For Early Stage Biotechnology Startup With Antibody Based TherapeuticsSelf-Employed Apr 2021 - PresentCollaborate with CROs to developed memory B cell expansion assays and bispecific antibody bioassays evaluating target engagement and cytolytic activity.
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Associate Principal Scientist, Discovery BiologyMerck Jan 2017 - May 2019Palo AltoCo-lead of pharmacology sub team responsible for generating and reviewing data involving antibody specificity screens and in-vitro bio-assay validation for T cell antigen receptor mimetic (anti-WT-1) in collaboration with Neatherlands Cancer Institute.
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Associate Principal ScientistMerck Research Labs Palo Alto Jan 2015 - May 2018Palo Alto, CaDeveloped alloreactive human CD4 and CD8 T cell clones and screened I/O antibodies to validate immuno-modulatory receptor target engagement for bispecific antibody programs. Responsible for isolation, phenotypic characterization and bio-assay screens of CD4 and CD8 clones from expanded tumor biopsies comparing mono vs. bispecific antibodies against PD-1 and LAG3
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Associate Principal Scientist, Protein SciencesMerck Research Labs Jul 2011 - Jan 2015Palo Alto, CaAntibody Engineering and bio-assay developer: murine antibody humanization, expression and characterization. Bi-specific antibody platform screeningBio-analytics assay development: target engagement and inter-cellular signalling
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Associate Principal Scientist, Protein EngineeringSchering Plough, Palo Alto, Ca Dec 2002 - Jul 2011Palo Alto, CaCloning, mutagenesis and expression and purification of murine and humanized therapeutic monoclonal antibodies(anti-IL10, anti-IL23,anti-IL23 receptor). Cloning, expression and bioassaycharacterization of therapeutic cytokines, cytokine receptors, Fc gamma receptors and bispecificantibody constructs
Robert Shields Skills
Robert Shields Education Details
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Biology/Biological Sciences, General
Frequently Asked Questions about Robert Shields
What company does Robert Shields work for?
Robert Shields works for Self-Employed
What is Robert Shields's role at the current company?
Robert Shields's current role is Bioanalytical assay developer for I/O and autoimmune antibody based therapeutics.
What is Robert Shields's email address?
Robert Shields's email address is ro****@****rck.com
What schools did Robert Shields attend?
Robert Shields attended Stanford University.
What are some of Robert Shields's interests?
Robert Shields has interest in Science And Technology, Education, Environment, Health.
What skills is Robert Shields known for?
Robert Shields has skills like Immunomodulatory Receptor Pharmacology, Cloning, Flow Cytometry, Immunoassay Development, Expression And Bioanalytical Characterization Of Protein Therapeutics, In Vitro Human T Cell Culture, Msd Cytokine And Immunoassay Development.
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Robert Shields
Well Seasoned Engineering Manager Specializing In Telecommunications Development And Materiel AcquisitionUnited States -
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Robert Shields
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Robert Shields
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