– Extended a mathematical model of drug release from polymeric microspheres to account for drug-polymer interactions.– Developed a novel model for reactive-oxygen species-mediated polymer degradation to account for the accelerated degradation and drug release obseved in vivo compared to in vitro– Reconstructed accurate blood glucose profiles from subcutaneous glucose monitors and developed a model for glucose monitor error– Developed a control scheme using moving horizon estimation and model predictive control to maintain critically-ill patients’ blood glucose levels within a target zone through continuous insulin and glucose infusions– Tested and tuned control scheme using a virtual patient platform with simulated noise using a model of glucose monitor error

– Worked on the development of mathematical models to describe the progression of severe sepsis– Built a mathematical model of a hemoadsorption device used to selectively remove key sepsis- related cytokines from the blood stream

– Synthesized and performed electrochemical characterization of polymer cholesteric liquid crystals using spectrophotometrcy, optical microscopy, interferometry, and electrochemial analyzation equipment