David Lee Email & Phone Number

Edison, Nj, Us

Target and biomarker identification of chemotherapeutic-resistant cancer cells through analysis of next-generation sequence (NGS) data o Assay selection/assay design (cytotoxic and genomic assays), protocol development, and sample analysis of human doxorubicin-resistant non-small cell lung cancer (NSCLC) cellsDeveloped and optimized liposomal formulation and delivery system with small molecules and nucleic acid o Formulated liposome encapsulating donepezil, memantine, and BACE-1 siRNA as a combination therapy o Measured characteristics of liposome using a dynamic light scattering analyzer, a UV-HPLC, a fluorescent reader, multi-color flow cytometryEstablished in-vitro and in-vivo biochemical assays for evaluating the safety and efficacy of liposomes for multiple routes of novel delivery administrations o Established ELISA, qPCR, and quantitative western blot protocols that analyzed human biomarkers from neuronal cells and brain tissues of Alzheimer’s model o Established cytotoxicity assay and liposome cellular internalization o Spearheaded strategies for dosing regimen and overall study parameters for in-vivo investigation with internal experts and external partners o Conducted intranasal delivery of small molecule and nucleic acid liposomes to evaluate humanized beta-amyloid plaque from APP/PS1 transgenic mice, developed Y-maze protocol, and assessed their behavioral activity o Assessed in-vitro and in-vivo data using Graphpad PrismProvided tactical/scientific mentorship to graduate/postgraduate scientist level

2015-2016 Post Doctorate PGY-1 resident2016-2017 Oncology Pharmacist2017-present Hospital pharmacist• Performed drug utilization review to identify therapy problems and optimize patient care• Compounded and dispensed pharmaceuticals including sterile and chemotherapy products• Provided drug information to other healthcare workers• Delivered pharmaceutical care in different healthcare settings and improved the medication use process• Effectively provided +30 medication and practice-related education and presentations to patients, healthcare professionals, and the community• Constructed +10 standard operating procedures (SOPs) of preparation and administration protocols for investigational drugs in clinical trials

Doctor Of Pharmacy - Pharmd

Education record